Question

In: Biology

Which of the following stages of cellular respiration makes the most ATP? glycolysis citric acid cycle...

Which of the following stages of cellular respiration makes the most ATP?

glycolysis

citric acid cycle

oxidative phosphorylation

Expert Solution

Citric acid cycle makes the most ATP i.e 24 ATP

In glycolysis ATP produced is 6ATP

In oxidative phosphorylation ATP produced is 6ATP.

GLYCOLYSIS:

In Glcolysis ATP producedproduced by substrate level phosphorylation:

Bisphosphoglyceric acid to Phosphoglyceric acid-2ATP

Phosphoenol pyruvic acid to Pyruvic acid-2ATP

But ATP is consumed for the phosphorylation of Glucose and Fructose-6-phosphate - (-2ATP)

Net gain of ATP in SLP of glycolysis is 2ATP

ATP generated from NADH in glycolysis- 4ATP

Therefore total ATP generated through Glycolysis is 6ATP.

OXIDATIVE PHOSPHORYLATION:

In the conversion of Pyruvic acid to Acetyl CoA 2NADH are produced each worth 3ATP.

So the number of ATP generated through Oxidative phosphorylation is 6ATP.

CITRIC ACID CYCLE:

ATP produced by Substrate level phosphorylation during conversion of Succinyl CoA to Succinic acid - 2 ATP

ATP produced from NADH during:

Conversion of isocitric acid to oxalosuccinic acid-6ATP (2×3ATP)

Conversion of alphaketoglutaric acid to Succinyl CoA -6ATP(2×3ATP)

Malic acid to Oxaloacetic acid -6ATP(2×3ATP)

ATP produced from FADH2 during the conversion of Succinic acid to Fumaric acid -4ATP (2×2ATP).

Therefore total ATP produced in Krebs cycle are 24ATP.

gladiator answered 1 year ago

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