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what are the five (5) core tests performed in a blood unit? According to World Health...

what are the five (5) core tests performed in a blood unit? According to World Health Organization

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Rh typing

The Rh (D) type of the transfusion recipient is determined by testing recipient red blood cells with anti-D

ABO typing

ABO typing involves testing the recipient’s red blood cells for the presence of A and B antigens using anti-A and anti-B antisera (forward grouping).

Antibody screening

Alloantibodies to antigens that are not present on an individual's red blood cells may develop in anyone who has been exposed to foreign red blood cell antigens through pregnancy or transfusion. To detect antibodies to non- group A or B antigens, a sample of the patient's plasma or serum is tested against selected commercial Type O red blood cells that express the majority of clinically significant antigens, other than A and B.

CROSSMATCH

The crossmatch is meant primarily to detect and prevent ABO incompatibility

Antibody identification

If a clinically significant antibody is detected in a recipient's plasma by screening technique, further testing is usually done to identify the antibody. This process, known as antibody identification, involves testing the plasma with a panel of commercial Type O red blood cells with known antigen expression

Nightingale answered 2 years ago
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