PART A: In a liver cell at 37 ?C the concentrations of both phosphate and glucose...

PART A:

In a liver cell at 37 ?C the concentrations of both phosphate and glucose are normally maintained at about 5 mM each. What would be the equilibrium concentration of glucose-6-phosphate, according to the above data?

ANS:

Equilibrium concentration =

1.2×10^?7 M

PART B:

This very low concentration of the desired product would be unfavorable for glycolysis. In fact, the reaction is coupled to ATP hydrolysis to give the overall reaction

ATP+glucose?glucose?6?phosphate+ADP+H+

What is ?G?? for the coupled reaction?

Express your answer to three significant figures and include the appropriate units.

ANS: -18.4 kJ/mol

PART C:

If, in addition to the constraints on glucose concentration listed previously, we have in the liver cell ATP concentration = 3 mM and ADP concentration = 1 mM, what is the theoretical concentration of glucose-6-phosphate at equilibrium at pH=7.4 and 37 ?C? Express your answer to three significant figures and include the appropriate units.

NEED HELP WITH PART C

Expert Solution

queen_honey_blossom answered 2 years ago

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