In: Biology
Suppose that a mammalian cell line is heterozygous at the sole locus encoding the cyclin dependent kinase of MPF. One allele encodes Active CdK, the other allele harbors a nonsense codon. Now, in one cell, a mutation occurs that introduces a frame shift into the active copy of this Cdk? What happens with this mutated cell?
It divides on
It gets stuck in G2
It gets stuck in G1
It gets stuck in S phase