Please explain Eukaryotic Transcription in DETAIL (Pol I, Pol II, Pol III, and their respective factors...

Please explain Eukaryotic Transcription in DETAIL (Pol I, Pol II, Pol III, and their respective factors involved)

Expert Solution

RNA polymerase I involved in synthesis of rRNA. Transcription yields 45S pre-rRNA which process to yield 28S, 18S, and 5.8S rRNAs. The promoter are recognised by UBF (upstream binding factor) and SL1 (selectivity factor 1) both recruit polymerase I to form an initiation complex. SL1 factor consists of TBP (transcription binding protein).

RNA polymerase II synthesis mRNA where it recognise sequence similar to TATAA box. Initially TFIID binds to TATA box, TFIID has TBP (TATA binding protein) which binds specifically to the TATAA consensus sequence. Then TBP binds TFIIB forms TBP-TFIB in the promoter region. Then RNA polymerase II binds with this complex with TFIIF.

RNA polymerase III synthesis tRNAs, 5S rRNA, and some of the small RNAs involved in splicing and protein transport. TFIIIA initiates assembly of a transcription complex through binding of DNA sequence in 5SrRNA promoter region. Then TFIIIC, TFIIIB, and the polymerase binds to that promoter region.

gladiator answered 2 years ago

Eukaryotic cells produce three distinct RNA polymerases: pol I, pol II, and pol III. Which of...

Eukaryotic cells produce three distinct RNA polymerases: pol I, pol II, and pol III. Which of the following statements is NOT true about eukaryotic RNA polymerases? A) Pol II, with twelve subunits on its own, is capable of initiating transcription. B) Pol III is responsible for the transcription of all tRNAs. C) Pol I carries out the transcription of the 45S pre-rRNA transcript. D) Pol III is responsible for the transcription of ribosomal 5S rRNA.

describe the process of Eukaryotic transcription in detail please. Thank you.

Explain what would happen during DNA replication if both DNA Pol I and DNA Pol III...

Explain what would happen during DNA replication if both DNA Pol I and DNA Pol III had high processivity. in writing no diagrams or pictures

what are the similarties and differences between bacterial, archael, and eukaryotic transcription ( using RNa pol...

what are the similarties and differences between bacterial, archael, and eukaryotic transcription ( using RNa pol II) initiation.

1. In DETAIL describe the assembly of the general transcription factors at a class II gene....

1. In DETAIL describe the assembly of the general transcription factors at a class II gene. Provide the important components of each complex, list the assembly in the correct order, and describe the function of each complex through generation of the open complex (10 pts). 2. Define the following terms, for proteins provide their function. Remember, providing an example is not a definition (1pt each). a. Consensus sequence b. RNaseH c. Ribonucleoprotein complex d. Transcriptional capacity

Eukaryotic Transcription Factors (TF) can be described as:

Eukaryotic Transcription Factors (TF) can be described as:a. Activators that recruit co-activators to initiate transcription of the geneb. cis-acting transcriptional elementsc. proteins that interact with the promoter/enhancer regions via DNA binding domainsd. multimeric components of nucleosomes

Explain the termination of Polymerase I, II, and III.

Explain in detail type I and III hypersensitivity

Fill in the blank- During eukaryotic transcription, the assembly of the general transcription factors begins with...

Fill in the blank- During eukaryotic transcription, the assembly of the general transcription factors begins with the binding of the factor________in a complex with the general transcription factor_________to DNA, causing a marked local distortion in the double helix. This factor binds at the DNA sequence called the________box, which is typically located 25 nucleotides upstream from the transcription start site. Once RNA polymerase II has been brought to the promoter DNA, it must be released to begin making transcripts. This release...

Eukaryotic transcription factors often bind to DNA at sites long distances from the transcription start site....

Eukaryotic transcription factors often bind to DNA at sites long distances from the transcription start site. These DNA regions are called:

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