Question

1) True or False

- K_eq for H₂O is << 1

- ΔG° is the Gibbs free energy of a reaction at equilibrium.

- All energy released from an exothermic reaction is available to do work in the cell.

- A reaction with an equilibrium constant of 2.4x10^-2 proceeds forward spontaneously under standard state conditions

- Enzyme active sites undergo conformational changes in order to bind optimally to their substrates.

- A reaction with a positive ΔG will proceed in a cell as long as it has an enzyme to catalyze the reaction.

Answer 1

1) True, Pure water can form both H+ and OH-. At 25 °Cthe equilibrium constant also called dissociation constant, Kw is  = 1.01 × 10-14

2) True, because the position of equilibrium corresponds to a minimum in the value of the Gibbs free energy and maximum value of entropy.

3) True, Exothermic reaction in cell is breakdon of glucose and produce ATPs in the respiration process and the energy released in the form of ATP is used to do work in cell

4) False, Under standard conditions,for a spontaneous process Keq and Kp should be greater than 1 and here keq is less than 1.

5) True, In order to bind to substrate optimally active site is induced to undergo conformational changes. Active site amino acids are highly conserved for the same enzyme between different species.

6) False, Reaction with positive delta G are endergonic reaction and require energy so will proceed in the cell if energy is available.