List the goals for each phase of the clinical trial: 1. Pre-clinical investigations 2. Phase I...

List the goals for each phase of the clinical trial:

1. Pre-clinical investigations

2. Phase I

3. Phase II

4. Phase III

5. Phase IV

Expert Solution

1. Pre-clinical trials: Test the effect of drugs on animal and human cell morphology and physiology, followed by testing on animals with similar target organs as humans

2. Phase I: A very small number of candidates are chosen to test the safety of the drug in humans, and to determine the dosage

3. Phase II: Test efficacy of the drug in a large group, with blind and double blind procedures to maintain tamper free results

4. Phase III: Tests effectiveness, adverse effects, additional benefits of the drug in various patients who are chosen based on pre-existing conditions which are targeted by the drug

5. Phase IV: This consists of continued research after the drug is released, providing new information about drug-drug and drug-food interactions, compare quality of life and measure cost-effectiveness of the drug

gladiator answered 2 years ago

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