Question

1. What is meant by lipid bilayers of platelets cells having a “sidedness” to them? Another way of stating this, is how do the inner and out leaflets compare to each other in the composition of the lipids and proteins

2. Blood clotting factors are found circulating in the blood. Why are they not constantly causing blood clots?

3. Phosphatidylserine (PS) provides the most active catalytic surface for forming coagulation factor complexes. PS is generally located on the cytoplasmic surface of blood and endothelia cell membranes. What would happen if PS was always located on the outside of the cell membrane?

4. How do the three enzymes described in the paper determine sidedness of the various types of phospholipids ?

Answer 1

Ans-The transverse asymmetry (sidedness) of phospholipids in plasma layer bilayers is very much portrayed, particular, effectively kept up and practically significant. Conversely, various investigations utilizing an assortment of procedures have reasoned that plasma layer bilayer cholesterol is either for the most part in the external handout or the internal flyer or is decently equally conveyed.

inner and out leaflets compare to each other in the composition of the lipids and proteins because of there polar or non-polar head

cloting is a hemostatis process of body and when the body loss blood after than the clotting factor activate than after the clotting occur.

if PS is present outside the cell membrane than cell is divide because it play a key role in cell cycle specifically in relation to apoptosis.

there are primary three kinds of membrane proteins: the first is essential layer protein that is for all time tied down or part of the layer, the subsequent sort is fringe film protein that is just incidentally joined to the lipid bilayer or to other necessary proteins, and the third one is lipid-moored proteins