Question

In: Biology

Outer hair cells contribute not only to amplification but also to the frequency tuning in the...

Outer hair cells contribute not only to amplification but also to the frequency tuning in the cochlea. What are some of the difficulties that might arise for people with cochlear hearing loss, due to these two factors? Why do hearing aids not solve all these problems?

Solutions

Expert Solution

The cochlea is a tiny, snail-shaped structure. It is the main organ of hearing and is part of your inner ear. Cochlear Damage means that all or part of your inner ear has been hurt. Damage to the cochlea typically causes permanent hearing loss.This is called sensorineural hearing loss (SNHL).

What are the causes ?

The causes of sensorineural hearing loss are varied but can be generally put into two categories: congenital and acquired.

Congenital hearing loss is present at birth and is the most common problem seen in newborn babies. It can be either inherited or caused by abnormal development in the fetal stages of life. Before the development of a vaccine, maternal rubella or German Measles was a common cause of congenital hearing loss.

Acquired hearing loss, which happens after birth, can be caused by a wide range of factors. These include trauma, presbycusis (age-related hearing loss), noise exposure from machinery or firearms, Meniere’s disease and meningitis. Ototoxic drugs - which damage the ear but may be necessary to treat some life-threatening medical conditions – can also trigger hearing loss. A tumour on the hearing nerve can cause the rarer neural hearing loss.

What happens when cochlear damage occurs?

Thousands and thousands of tiny nerves called ‘hair cells’ line the inside of the snail-shaped structure, the cochlea. Each hair cell is responsible for picking up a different sound, sort of like keys on a piano, but on a much more detailed scale. All of the hair cells work in concert to code the incoming sound and send it on to the brain, where sound is heard and understood.

magine the tiny hair cells, standing tall and waving back and forth as sound comes into the ear. All of a sudden, an extremely loud sound enters the ear and the cochlea. The hair cells are hit with sound so hard that the hair cells are bent, broken, and in some cases, totally sheared off. Once this cochlear damage occurs, the damage is done. Hair cells in the cochlea are not able to regenerate themselves. Unlike your skin, hair, and many other cells in the body, once cochlear damage occurs, there’s no ‘growing’ back.

Difficulties in cochlear hearing loss

Since the inner ear is not directly accessible to instruments, identification is by patient report of the symptoms and audiometric testing. Of those who present to their doctor with sensorineural hearing loss, 90% report having diminished hearing, 57% report having a plugged feeling in ear, and 49% report having ringing in ear (tinnitus). About half report vestibular (vertigo) problems.

Most cases of SNHL present with a gradual deterioration of hearing thresholds occurring over years to decades. In some, the loss may eventually affect large portions of the frequency range. It may be accompanied by other symptoms such as ringing in the ears (tinnitus) and dizziness or lightheadedness (vertigo).

Frequent symptoms of SNHL are loss of acuity in distinguishing foreground voices against noisy backgrounds, difficulty understanding on the telephone, some kinds of sounds seeming excessively loud or shrill, difficulty understanding some parts of speech (fricatives and sibilants), loss of directionality of sound (especially with high frequency sounds), perception that people mumble when speaking, and difficulty understanding speech.

Why do hearing aids not solve all these problems?

Hearing aids can help most people with mild to moderate sensorineural hearing loss in both ears. For more severe levels of hearing loss, sometimes hearing aids just do not help enough. This is because sensorineural hearing loss causes sounds to become distorted. Amplifying sounds through hearing aids makes them sound louder, but not necessarily clearer. Even good quality hearing aids can sound distorted if the inner ear is severely damaged.

Hearing aids amplify sounds, if the cochlea is severely damaged and many hair cells are missing, amplified sound won’t get past the ‘relay station’ (i.e. the hair cells in the cochlea), to be sent on to the brain.


Related Solutions

What is an adaptive advantage of signal amplification within cells?
What is an adaptive advantage of signal amplification within cells?
Briefly explain (less than 50 words/cell), the cause, origin, outer/inner hair cell functions, frequency processing, intensity...
Briefly explain (less than 50 words/cell), the cause, origin, outer/inner hair cell functions, frequency processing, intensity coding, and bone/air conduction thresholds in the following: Noise Induced Hearing Loss Cause (Congenital or acquired or both)? Origin? Outer Hair Cell Function? Inner Hair Cell Function? Frequency Selectivity or processing? Intensity coding? Bone conduction thresholds? Air conduction thresholds? Otoacoustic emissions? Speech recognition in quiet? Speech recognition in noise?
You have a tuning fork, called tuning fork A of unknown frequency. you know that when...
You have a tuning fork, called tuning fork A of unknown frequency. you know that when it vibrates, it has a maximum amplitude of 0.002ft. Tuning fork B, which has a period of 0.05s causes tuning for A to vibrate with an amplitude of 0.01ft. Tuning for C which has a period of 0.2s causes tuning fork A to vibrate with an amplitude of 0.015ft. What is the natural frequency of tuning fork A?
A tuning fork on a movable cart is vibrating at a frequency of 1500 Hz. As...
A tuning fork on a movable cart is vibrating at a frequency of 1500 Hz. As you are walking past the cart at 2 m/sec, the cart begins accelerating uniformly in the direction you’re walking. When it is 20 m in front of you, the sound of the tuning fork is heard to be at a frequency of 1380 Hz. Knowing that the air temperature at your location is 23.6°C, determine the acceleration of the cart.
Design an active low pass filter with a corner frequency of 50 Hz and amplification of 10
 Design an active low pass filter with a corner frequency of 50 Hz and amplification of 10. Pick the values of the resistor and capacitor based on your own judgement to keep the cost reasonably low (simpler circuit design with less components is better).
In the organ of corti, what membrane is attached to the hair cells
In the organ of corti, what membrane is attached to the hair cells
write a program in c++ to design a tuning circuit for a given frequency bond using...
write a program in c++ to design a tuning circuit for a given frequency bond using a variable capacity to determine the value of an inductance required for a given frequency range
A tuning fork generates sound waves with a frequency of 230 Hz. The waves travel in...
A tuning fork generates sound waves with a frequency of 230 Hz. The waves travel in opposite directions along a hallway, are reflected by walls, and return. The hallway is46.0 m long and the tuning fork is located 14.0 m from one end. What is the phase difference between the reflected waves when they meet at the tuning fork? The speed of sound in air is 343 m/s. (Ans in degrees)
How do hair cells work and what role do they play in hearing? What role does the basilar membrane play in frequency diserimination?
How do hair cells work and what role do they play in hearing? What role does the basilar membrane play in frequency diserimination? 
A group of bird embryos was studied to see if the hair cells in cochlea were...
A group of bird embryos was studied to see if the hair cells in cochlea were able to regenerate after trauma. The first group of bird embryos was treated with growth factors similar to brain-derived neurotrophic factor molecules. The second group of bird embryos had specialized growth genes introduced into their genomes through a virus. The third group was untreated and left to develop without growth factors and gene therapy. The total number of hair cells per cochlea was determined...
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT