An enzyme contains an active site aspartic acid with a pka=5.0 which acts as a general...

An enzyme contains an active site aspartic acid with a pka=5.0 which acts as a general acid catalyst. Draw the curve of enzyme activity vs. pH for the enzyme (assume the protein is stably folded between pH 2-12 and that the active site Asp is the only ionizable residue involved in catalysis).Explain the shape of the curve

Expert Solution

queen_honey_blossom answered 2 years ago

Which of the following located in the active site of the enzyme chymotrypsin participates in acid-base...

Which of the following located in the active site of the enzyme chymotrypsin participates in acid-base chemistry? The side chain oxygen of serine The amide group of glycine The hydrophobic pocket Histidine The amide group of serine

Which of the following binds to the active site of an enzyme?

Which of the following binds to the active site of an enzyme? water product substrate any other enzyme none of the above

The active site of an enzyme is a small portion of the enzyme molecule What is...

The active site of an enzyme is a small portion of the enzyme molecule What is the function of the rest of the huge molecule? Check all that apply. To pass through cell membranes. To provide sites for enzyme control and regulation. To hold the substrate in place. To stabilize the three-dimensional structure of the enzyme. To align the active-site functional groups that catalyze the reaction.

1. The active site of an enzyme usually consists of a pocket on the enzyme surface...

1. The active site of an enzyme usually consists of a pocket on the enzyme surface lined with the amino acid side chains necessary to bind the substrate and catalyze its chemical transformation. Carboxypeptidase, which sequentially removes the carboxyl-terminal amino acid residues from its peptide substrates, consists of a single chain of 307 amino acids. The two essential catalytic groups in the active site are furnished by Arg145 and Glu270 . a. How many amino acid residues apart are these...

1.When the substrates bind to the active of an enzyme, the active site changes shape. This...

1.When the substrates bind to the active of an enzyme, the active site changes shape. This is an example of: a) lock & key model; b) inhibitor model; c) allosteric model; d) induced fit model; e) none. 2. The change in free energy at equilibrium is: a) increased; b) decreased; c) no net change 3. You have a gram of each of the following: bacon grease, lean ground turkey and bread. Which on has more potential energy and why? a)...

Understand the following enzymatic terms: substrate, enzyme, active site, induced fit, enzyme specificity, product, enzyme /...

Understand the following enzymatic terms: substrate, enzyme, active site, induced fit, enzyme specificity, product, enzyme / substrate complex, cofactors and coenzymes

In the active site of an enzyme, are Val and Ala residues found? True or false?

A zinc ion in the active site of an enzyme can speed up the reaction by:...

A zinc ion in the active site of an enzyme can speed up the reaction by: A. Making a bound water molecule a more powerful nucleophile by drawing electron density toward itself and facilitating deprotonation of the water B. Orienting substrates for reaction C. Stabilizing an anionic intermediate D. All of these E. None of these The role of serine at the active site of serine proteases is to act as a ___ catalyst, while the histidine residue serves as...

describe how an enzyme interacts with its substrate. define active site

What are enzymes? What is the active site of an enzyme? What does the term substrate...

What are enzymes? What is the active site of an enzyme? What does the term substrate mean?

Question