Question

Cacioppo and Freberg (2013, p. 21-22) revealed that patients with schizophrenia were a population segment subjected to research without restrictions. How do these ethical and moral injustices support the need for regulation?

Answer 1

Patients with schizophrenia were a population segment subjected to research without restriction

  Schizophrenia is a severe mental disorder that affects how a person thinks, feels, and behaves. People with schizophrenia may seem like they have lost touch with reality. Although schizophrenia is not as common as other mental disorders, the symptoms can be very disabling.   

There are lots of amendment are made in regards with experimentation with human subjects are as follows :-----Debate on the ethics of experiment with human subjects essentially began during the post–World War II where.......

The nuremburg code, prepared and was perhaps the first official document that called for the consent of individuals participating in research. Here, the basic principles of ethical research were stipulated, including the importance of voluntary consent, the protection of research participants from harm, and the freedom to withdraw from participation. This was followed by the Declaration of Helsinki, on the importance of research protocols, protection of confidentiality. The first broad set of federal guidelines was enacted in 1981 and was based on the principles outlined in the Belmont Report. This report identified three major principles in evaluating research respect for persons; beneficence; and justice.

Likewise for schizophrenia also it is said that Ethical concerns about schizophrenia research have been raised, for the most part, because of concerns about the decision-making capacity of the potential research participants. Schizophrenia is a disorder of disturbed thinking, and so it was reasoned that if thinking is disturbed, then capacity to consent is likely to be compromised. As a result, individuals with schizophrenia have long been considered a vulnerable population in the research setting. In this it covers main areas where ethical issues are there, and continue in schizophrenia research: competency of participants and informed consent; early intervention with prodromal patients; medication withdrawal and medication-free protocols; exclusion of suicidal patients from research on schizophrenia. Our intention is to highlight the progress that has been made in each of these areas, as well as several issues that in our view require additional consideration.

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