Question

In: Anatomy and Physiology

If the LDL-Cholesterol is to be calculated by the Friedewald formula, which of the following measurements...

If the LDL-Cholesterol is to be calculated by the Friedewald formula, which of the following measurements needs to be preformed by a chemical method?

A. All of these mentioned here

B. HDL-C

C. Triglycerides

D. Total Cholesterol

(I answered B and it was incorrect)

Solutions

Expert Solution

Question: If the LDL-Cholesterol is to be calculated by the Friedewald formula, which of the following measurements needs to be preformed by a chemical method?

A. All of these mentioned here

B. HDL-C

C. Triglycerides

D. Total Cholesterol

Answer: A. All of these mentioned here

Friedewald formulae for estimating LDL-C: LDL-C = Total cholesterol – HDL-C – [Tg/5]

All concentrations are in the unit mg/dL.

VLDL-C = [Plasma Triglycerides / 5], the ratio of the TG to cholesterol is a constant at about 5:1.

LDL-C: Low-density lipoprotein cholesterol (LDL-C)

HDL-C: High-density lipoprotein cholesterol (HDLC)

TC: Total cholesterol (TC)

TG: Triglycerides

Limitations of the Friedewald equation is that the Plasma Triglycerides concentration should not exceed 400 mg/dL.

Friedewald formula not valid if Triglycerides > 400 mg/dL.


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