In: Anatomy and Physiology
If the LDL-Cholesterol is to be calculated by the Friedewald formula, which of the following measurements needs to be preformed by a chemical method?
A. All of these mentioned here
B. HDL-C
C. Triglycerides
D. Total Cholesterol
(I answered B and it was incorrect)
Question: If the LDL-Cholesterol is to be calculated by the Friedewald formula, which of the following measurements needs to be preformed by a chemical method?
A. All of these mentioned here
B. HDL-C
C. Triglycerides
D. Total Cholesterol
Answer: A. All of these mentioned here
Friedewald formulae for estimating LDL-C: LDL-C = Total cholesterol – HDL-C – [Tg/5]
All concentrations are in the unit mg/dL.
VLDL-C = [Plasma Triglycerides / 5], the ratio of the TG to cholesterol is a constant at about 5:1.
LDL-C: Low-density lipoprotein cholesterol (LDL-C)
HDL-C: High-density lipoprotein cholesterol (HDLC)
TC: Total cholesterol (TC)
TG: Triglycerides
Limitations of the Friedewald equation is that the Plasma Triglycerides concentration should not exceed 400 mg/dL.
Friedewald formula not valid if Triglycerides > 400 mg/dL.