Question

(a) Given that any given meiosis will produce two types of gametes one with two sex chromosomes and one with only one, what combinations of sex chromosomes would you find in the sperm of a Klinefelter's man and in what proportion?

(b) If a Klinefelter’s man mates with a typical (XX) female, what would you expect for the genetic composition of their children? What genotypes would you expect for all their possible children? Indicate the relative proportions of the genotypes and whether you think they would be more male or more female.

Answer 1

(a) klinefilter syndrome peoples have XXY genotype they gained normally an extra X chromosome due to non-disjunction during meiosis .Particularly they have the both sexes male and female XY( the Y chromosome is important for the maleness so they have the primary male characters the reproductive organs ) but biologically sterile  .And extra X chromosome is enough for the secondary female characters which includes the breast enlargement (gynecomastia), decreased muscle mass, decreased bone density, and a reduced amount of facial and body hair. so the combination of sex chromosome in the klinefilter patients is almost 50:50 , as mostly mens are affected from this.

They have 2 sex combination one is XY making it male and X chromosome making it female

(b) by crossisng the klinefilter person with the normal female

(X ) (X) ( XY) ( X ) 2 normal females , and 2 XXY klinefilter males .

there is equal chances of male and female but females are normal while the male are affected with kline filter syndrome .

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