These transcription factors only induce the transcription of genes involved in maintaining the stem-cell state, and...

These transcription factors only induce the transcription of genes involved in maintaining the stem-cell state, and not genes with other functions. Which of the following terms best describes these proteins?

		Distal cis-elements
		Proximal cis-elements
		General trans-elements
		Regulatory trans-elements

Expert Solution

Answer) Distal cis-elements.

Reason: We know that Sox2 is one of the key gene involved in maintaining the stem cell state. taking its example, there is cis elements regulating the expression of Sox2 gene. and this cis elements are not present in proximity rather they are Sox2 distal-enhancer cluster which helps in maintaining stem cell state and in regulating the differentiation potential of embryonic stem cell.

gladiator answered 2 years ago

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