Which of the following statements is incorrect? Select all that apply.

The eukaryotic ribosome uses both the 5' cap and the 3' tail to correctly position the ribosome on the initation codon

GTP is hydrolyzed by aminoacyl-tRNA synthetases to prepare amino acids for attachment to tRNAs

The peptidyl-transferase activity of the ribosome is catalyzed by one of the protein domains of the large ribosomal subunit

The Shine-Dalgarno consensus sequence is located downstream of the initiation codon and base pairs with the 16S rRNA of the large ribosomal subunit

Ef-Tu catalyzes the exchange of GDP for GTP on Ef-Ts

Large and small ribosomal subunits are infrequently found in their free, uncomplexed forms in a prokaryotic cell

Solutions

Expert Solution

The incorrect statements are:

GTP is hydrolyzed by aminoacyl-tRNA synthetase to prepare amino acids for attachment to tRNAs

(ATP is hydrolyzed by aminoacyl-tRNA synthetase to prepare amino acids for attachment to tRNAs)

The peptidyl transferase activity of the ribosome is catalyzed by one of the protein domains of the large ribosomal subunit.

(The primary peptidyl transfer, is a ribozyme activity encoded in large subunit)

The shine Dalgarno consensus sequence is located downstream of the initiation codon and base pairs with the 16S rRNA of the large ribosomal subunit.

(The shine Dalgarno consensus sequence is located upstream of the initiation codon and base pairs with the 16S rRNA of the small ribosomal subunit)

Ef-Tu catalyzes the exchange of GDP for GTP on Ef-Ts

(EF-Ts catalyzes the exchange of GDP for GTP on EF-Tu and thus regenerates EF-TuGTP).

gladiator answered 1 year ago

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