Question

In: Biology

all of the following can lead to cancer except: a) hereditary factos b) viruses c) natural...

all of the following can lead to cancer except:

a) hereditary factos

b) viruses

c) natural killer cells

d) methylation of the genome

Solutions

Expert Solution

Answer

The correct answer is option c. Natural killer cells don't lead to cancer.

Natural killer cells - they're kind of white blood cell and a part of the innate immune system. Natural Killer cells play a serious role within the host-rejection of both tumors and virally infected cells. As innate immune cells, natural killer (NK) cells are distinctive and play important functions in cancer immune surveillance. NK cells can eliminate a range of abnormal or stressed cells without previous sensitization, and even preferentially kill stem-like cells or cancer stem cells

.option a is incorrect because hereditary factors result in the development of cancer.

When cancer happens due to an inherited gene mutation, it's mentioned as hereditary cancer. examples of tumor suppressor genes include BRCA1, BRCA2, and p53 or TP53. Germline mutations in BRCA1 or BRCA2 genes increase a woman's risk of developing hereditary breast or ovarian cancers and a man's risk of developing hereditary prostate or breast cancers.

.option b is incorrect because viruses will result in cancer. once viruses cause an infection, they spread their DNA, affecting healthy cells' genetic makeup and probably causing them to turn into cancer.

.option d is incorrect because methylation of the genome results in cancer.

Methylation among the promoter regions of tumor suppressor genes causes their silencing, and methylation among the gene itself will induce mutational events. These mechanisms might play a basic role in precipitating the event of a large and diverse range of human cancers.


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