explain why the signal enhancement can result in a transient NOESY experiment. (hint: you might find...

explain why the signal enhancement can result in a transient NOESY experiment. (hint: you might find it easier to answer this question if you draw an energy diagram)

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Expert Solution

The nuclear Overhauser effect (NOE) is the transfer of nuclear spin polarisation from one population of spin-active nuclei (e.g. 1H, 13C, 15N etc.) to another via cross-relaxation.

NOESY is useful for determining which signals arise from protons that are close to each other in space even if they are not bonded. A NOESY spectrum yields through space correlations via spin-lattice relaxation. NOESY also detects chemical and conformational exchange. It is called EXSY when used for this purpose.

genius_generous answered 2 hours ago

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