explain why the signal enhancement can result in a transient NOESY experiment. (hint: you might find...

explain why the signal enhancement can result in a transient NOESY experiment. (hint: you might find it easier to answer this question if you draw an energy diagram)

Expert Solution

The nuclear Overhauser effect (NOE) is the transfer of nuclear spin polarisation from one population of spin-active nuclei (e.g. 1H, 13C, 15N etc.) to another via cross-relaxation.

NOESY is useful for determining which signals arise from protons that are close to each other in space even if they are not bonded. A NOESY spectrum yields through space correlations via spin-lattice relaxation. NOESY also detects chemical and conformational exchange. It is called EXSY when used for this purpose.

genius_generous answered 1 month ago

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