Question

In: Statistics and Probability

A pharmaceutical company claims that its new drug reduces systolic blood pressure. The systolic blood pressure...

A pharmaceutical company claims that its new drug reduces systolic blood pressure. The systolic blood pressure (in millimeters of mercury) for nine patients before taking the new drug and 2 hours after taking the drug are shown in the table below. Is there enough evidence to support the company's claim? Let d = (blood pressure before taking new drug) − (blood pressure after taking new drug). Use a significance level of α = 0.05 for the test. Assume that the systolic blood pressure levels are normally distributed for the population of patients both before and after taking the new drug.

Patient 1 2 3 4 5 6 7 8 9

Blood pressure (before)

199 166 183 197 200 192 190 179 200

Blood pressure (after)

183 151 172 174 185 170 180 173 185

Step 1 of 5: State the null and alternative hypotheses for the test.

Step 2 of 5: Find the value of the standard deviation of the paired differences. Round your answer to one decimal place.

Step 3 of 5: Compute the value of the test statistic. Round your answer to three decimal places.

Step 4 of 5: Determine the decision rule for rejecting the null hypothesis H0. Round the numerical portion of your answer to three decimal places.

Step 5 of 5: Make the decision for the hypothesis test.

Solutions

Expert Solution

Before After Difference
199 183 16
166 151 15
183 172 11
197 174 23
200 185 15
192 170 22
190 180 10
179 173 6
200 185 15
Total 133

Step 1:

A pharmaceutical company claims that its new drug reduces systolic blood pressure.

The null and alternative hypothesis is

Step 2:

Sample standard deviation of difference = = 5.4

Step 3:

Sample size = n = 9

Sample mean of difference = = 14.78

Test statistic is

Step 4:

Degrees of freedom = n - 1 = 9 - 1 = 8

Critical value = 1.860 ( Using t table)

Step 5:

Test statistic > critical value we reject null hypothesis.

Conclusion:

A pharmaceutical company claims that its new drug reduces systolic blood pressure is right.


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