In: Statistics and Probability
A pharmaceutical company claims that its new drug reduces systolic blood pressure. The systolic blood pressure (in millimeters of mercury) for nine patients before taking the new drug and 2 hours after taking the drug are shown in the table below. Is there enough evidence to support the company's claim? Let d=(blood pressure before taking new drug)−(blood pressure after taking new drug). Use a significance level of α=0.05 for the test. Assume that the systolic blood pressure levels are normally distributed for the population of patients both before and after taking the new drug.
Patient 1 2 3 4 5 6 7 8 9
Blood pressure (before) 199 164 173 201 174 163 172 155 182
Blood pressure (after) 186 153 147 189 167 151 154 142 162
Step 1 of 5: State the null and alternative hypotheses for the test
Step 2 of 5: Find the value of the standard deviation of the paired differences. Round your answer to one decimal place.
Step 3 of 5: Compute the value of the test statistic. Round your answer to three decimal places.
Step 4 of 5: Determine the decision rule for rejecting the null hypothesis H0. Round the numerical portion of your answer to three decimal places.
Step 5 of 5: Make the decision for the hypothesis test. Reject or Fail to Reject
Step 1 of 5: The null and alternative hypotheses for the test are as below
H0 : There is no sufficient evidence that new drug reduces systolic blood pressure.
H1 : There is sufficient evidence that new drug reduces systolic blood pressure.
Consider, 
is diffrence between the both population means that is (
)
Using parameter the null and alternative hypotheses for the test


Step 2 of 5: We find the value of the standard deviation of the paired differences using following table
Let,
= Blood pressure (before)
= Blood pressure (after)
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| 199 | 186 | 13 | 169 |
| 164 | 153 | 11 | 121 |
| 173 | 147 | 26 | 676 |
| 201 | 189 | 12 | 144 |
| 174 | 167 | 7 | 49 |
| 163 | 151 | 12 | 144 |
| 172 | 154 | 18 | 324 |
| 155 | 142 | 13 | 169 |
| 182 | 162 | 20 | 400 |
|
|
2196 |
We find mean (
)
and standard deviation (
)
using following formula

(Round answer up to 1 decimal places)
Step 3 of 5: We compute the value of the test statistic using following formula

If we used
then test statistic are as below
(Round answer up to 3 decimal places)

Or
If we used
then test statistic are as below
(Round answer up to 3 decimal places)

Test statistic
If we used
If we used
(Because in the above question it is
not given the answer of mean (
)
round up to which decimal places)
Step 4 of 5: We determine the decision rule for rejecting the null hypothesis H0 are as below
First we find critical value of t using t table whose level of significance = α = 0.05 (For one tailed test) and
degrees of freedom = n - 1 = 9 - 1 = 8
Critical value of t = 1.860
We comparing above critical value of t with the test statistic and take decision about the reject or do not reject the null hypothesis H0 are as below
If test statistic t
critical value of t then we reject the null hypothesis
H0 otherwise we fail to reject the null hypothesis
H0.
Here, Test statistic
or
Critical
value of t = 1.860
Step 5 of 5: We make the decision for the hypothesis test are as below
Here, Test statistic
or
Critical
value of t = 1.860
We reject the null hypothesis H0.
That is, There is sufficient evidence that new drug reduces systolic blood pressure.
Or A pharmaceutical company claims that its new drug reduces systolic blood pressure is true.