Why is AMP a good indicator of the ATP level in the cell?

Solutions

Expert Solution

Answer. ATP undergoes hydrolysis to form ADP and Pi. Further, ADP (Adenosine di phosphate) breaks down to form ADP and Pi. During both these steps, huge amount of energy is released which is used by the body for various physiological processes.

The amount of AMP present in a cell is directly proportional to the amount of ATP, because as stated above it is synthesized from the ATP itself plus AMP also helps in deriving energy when the energy demand of the body is high i.e. both provides energy to the cell.

At the time of high energy requirements like excess physical activity, presence of AMP in a cell activates the enzyme, AMP-activated protein kinase(AMPK) , to derive more energy to the body. Phosphorylation of AMPK takes place as AMP binds to it. Some studies say that the amount of AMP:ATP in a cell also triggers the activation of the AMPK enzyme.

By the activation of AMPK, a series of reactions takes place which favours the catabolic pathway but hinders the anabolic pathway to regenerate ATP.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Regarding ATP/AMP concentrations in the cell: a. Upon ATP hydrolysis, why might the AMP increase affect...

Regarding ATP/AMP concentrations in the cell: a. Upon ATP hydrolysis, why might the AMP increase affect the cell more than the ATP decrease? b. What role does AMP kinase play? c. What pathways would be activated by high ATP/low AMP, energy producing or energy storage? d. What pathways would be activated by low ATP/high AMP, energy producing or energy storage?

True or false? Substrate-level phosphorylation is the phosphorylation of AMP by ATP.

if an ATP molecule is hydrolyzed (by two water molecules) all the way to AMP (and...

if an ATP molecule is hydrolyzed (by two water molecules) all the way to AMP (and two Pi) in two steps, how many total kcal/mol of energy could be released? Explain. Using this equation. ADP + H2O -> AMP + Pi + 7.3 kcal/mo

1. Why is ATP synthase considered an active transporter? 2. Why is deleterious to a cell...

1. Why is ATP synthase considered an active transporter? 2. Why is deleterious to a cell that DNA can be crosslinked, which forms covalent bonds between the two strands? 3. Describe all of the negative and positive controls used in the Pasteur experiment that disproved spontaneous generation, and briefly describe why each was included. 4. Why is a pH indicator used in cell culture media? 5. In biology we describe 10 important universal features of cells, #7 is that life...

Gluconeogenesis is favored when citrate levels are , when AMP levels are , and when ATP...

Gluconeogenesis is favored when citrate levels are __________, when AMP levels are __________, and when ATP levels are __________. Select one: a. low; low; high b. high; low; high c. low; high; low d. high; high; low

Is it consumerism good behaivor for country level? Why?

1. Are proteins, ATP, enzymes, or ribozymes responsible for doing work in the cell? Why? 2....

1. Are proteins, ATP, enzymes, or ribozymes responsible for doing work in the cell? Why? 2. Can glycolysis run in reverse? 3. Is the role of stomach acids to degrade, denature, synthesize, or inactivate proteins? 4. What is the sugar backbone of DNA generated by, phosphodiester bonds, peptide bonds, glycosidic bonds, or hydrogen bonds? 5. Proteins destined for cell export are synthesized in the nucleus, cytoplasm, mitochondria, or ER?

Researchers studied the relationship between glucose concentration, oxygen level, and ATP production in one type of mammalian cell.

Researchers studied the relationship between glucose concentration, oxygen level, and ATP production in one type of mammalian cell. Cells were isolated and cultured in growth medium containing either 1.5mM glucose or 25 mM glucose and at oxygen levels that varied from 0% to 21%. The researchers determined the concentration of ATP per cell under the different conditions. The ATP concentrations are shown as relative to the maximum ATP concentration obtained when cells were cultured in the presence of 25 mMglucose and 21% oxygen, standard culture conditions. The data are...

If the concentration of ATP in an E. coli cell is 4.8 mM, how many ATP...

If the concentration of ATP in an E. coli cell is 4.8 mM, how many ATP molecules are in a rod-shaped E. coli cell that is 2.1 micrometers long and 0.6 micrometers in diameter? Enter your answer to the nearest ones.

. Explain how glycogen phosphorylase is regulated by AMP, ATP, G6Pand phosphorylation/dephosphorylation? What is the physiological...

. Explain how glycogen phosphorylase is regulated by AMP, ATP, G6Pand phosphorylation/dephosphorylation? What is the physiological significance of these control mechanisms? b. What are the effects of the following on the rates of glycogen synthesis and degradation? (a) increasing the Ca2+ ion concentration, (b) increasing the ATP concentration, (c) inhibiting adenylate cyclase, (d) increasing the epinephrine concentration, (e) increasing the AMP concentration. Explain.

Subjects