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What is the difference between immune checkpoint modulators and immune cell therapy? Explain giving examples for...

What is the difference between immune checkpoint modulators and immune cell therapy? Explain giving examples for each

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Expert Solution

  • immune check points are regulators of the immune system . these pathways are crecial for self - tolerance which prevents the immune system from attacking cells indiscriminiately ,    ex -   glioblastoma is the most comon primary brain tumour in adult prognosisis poor ; even with current glod - standard first line treatment - maximal safe resection and combination of radiotherapy with temozolomide chemotherapy .
  • immune therapy involves engineering patients own immne cells to recognise and attack their tumours and although this approach called adoptive cell transfer   ,      adoptive cell therapy for cancer is a form of transfusion   therapy , consisting of the infusion of various maure T cells , the cancer where the disease is unique to the indiidual , the adoptive T cell therapy is a personalised treatment .   immune cell therapy treatment become safe , effecting and cost effective , it is a new technology.

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