Question

The Central Dogma of Biology states that DNA is turned into RNA, which is turned into proteins. Is this rule infallible? Think of RNA viruses and telomeres when writing your response.

Answer 1

according to the central dogma of molecular biology.

DNA replicates to produce DNA, DNA is transcribed to produce mRNA, mRNA is translated to produce protein.

this rule is not complete, in RNA viruses, some RNA viruses are retroviruses, it uses reverse transcriptase to produce DNA from RNA, the central dogma of molecular biology does not give information about this process.

some RNA viruses have negative strand, so those viruses use RNA dependent RNA polymerase to produce + strand RNA which can be translated, similarly RNA viruses with positive-strand RNA uses RNA dependent RNA polymerase to produce negative-strand RNA which can be used as a template for the synthesis of + strand RNA, so RNA can be used as a template for the synthesis of RNA. Central Dogma of molecular biology does not give this information.

In the synthesis of telomeres, the telomerase enzyme contains RNA sequence which is used as the template to synthesize DNA, this is similar to Reverse transcription, which uses RNA as a template to make DNA.

Information in the Central Dogma of molecular biology are correct only but it is incomplete, it does not accout for the reverse transcriptase reaction, and the synthesis of RNA using RNA template.