Question

Describe the connection between map distances and recombination rates between three X-linked genes.

Answer 1

Answer- Higher recombination rates between two linked loci on the x chromosome often correspond to a larger map distance between the loci.

the longer the expanse of DNA between the loci would lead to a higher probability of a recombination occurring in that interval during meiosis, than if the loci were much closer together.

Interference is the reduction of double recombination events due to a single recombination event blocking the occurrence of a second recombination event in nearby intervals of DNA. So the recombination rates within the short intervals can't be added up to calculate distances over large intervals of DNA due to interference. the recombination rates within large intervals of DNA calculated from phenotype or genotype data will not accurately reflect the distance between the loci due to masking of single crossovers events with double crossover events.

So as the map distance between markers increases so does the frequency of double recombination. at recombination rate of 0.5 markers are functionally unlinked.