Question

In: Biology

What is FRAT? What role does FRAT play in the nuclear export?

What is FRAT? What role does FRAT play in the nuclear export?

Solutions

Expert Solution

FRAT is frequently rearranged T lymphomas.

They are associated with the GSK-3 ( Glycogen synthase kinase-3) nuclear export. The FRAT contain specialised sequence that support in GSK-3 nuclear export. FRAT contain GSK-3 binding protein that bind with the GSK-3 and export from the nucleus.


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