In: Biology
It can be argued that almost all diseases have, at their root, a cellular basis. This means we can typically trace every genetic or acquired condition to a problem in a specific type of cell. Is it possible, however, that these diseases/conditions/traits can actually be traced as far as the organelle level? Explore this possibility.
Ans: II Please give ratings II
Yes, it's true that we could trace genetic or acquired condition
to a disease through a specific way. Each organelle of cell play a
crucial role in performing cellular activities. for instance ,
inclusion cell disease happen because of malfunctioning of the
Golgi bodies, that play a crucial role in post translational
modification.Other example might be , defect within the
mitochondria gene could lead on to the genetic diseases transfer
from mother to the kids.
Each cell type found within the organism performs a various and
unique set of functions, the disruption of which may result in
disease. Identifying the cell types that contribute to the event
ofa disease is vital in understanding its etiology. Thousands of
genes that influence human disease are identified through linkage
analysis, genome-wide association studies and genome sequencing .
In many cases, the cell types that genes directly affect and by
which promote disease development have yet to be characterized or
are still debated. Identification of those cell types will further
our understanding of the genetic basis of those diseases and also
the underpinning molecular pathways and processes. However,
currently there exists no systematic mapping between cell types and
also the diseases they'll cause.