Question

(20.48) There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that they can be harnessed to use the body's immune system to treat cancer. One study investigated the use of a T cell-engaging antibody, blinatumomab, to recruit T cells to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study) and after 20 days on blinatumomab for 6 subjects in the study. The difference (after 20 days minus baseline) is the response variable. Baseline 0.04 0.02 0 0.02 0.31 0.42 After 20 days 0.18 0.37 0 0.15 1.12 0.34 Difference 0.14 0.35 0 0.13 0.81 -0.08

Do the data give evidence at the 5 % level that the mean count of T cells is higher after 20 days on blinatumomab?

The test statistic is t = _____(±0.001)

Yes

No

Answer 1