Question

(20.48) There is evidence that cytotoxic T lymphocytes (T cells) participate in controlling tumor growth and that they can be harnessed to use the body's immune system to treat cancer. One study investigated the use of a T cell-engaging antibody, blinatumomab, to recruit T cells to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study) and after 20 days on blinatumomab for 6 subjects in the study. The difference (after 20 days minus baseline) is the response variable.

Baseline	0.04	0.02	0	0.02	0.35	0.4
After 20 days	0	0.37	1.2	0.05	1.02	0.24
Difference	-0.04	0.35	1.2	0.03	0.67	-0.16

Do the data give evidence at the 1 % level that the mean count of T cells is higher after 20 days on blinatumomab?

The test statistic is t = _____ (±±0.001)

What is _____?

Answer 1