disease that is caused due to the disorders associated with the Golgi body

Solutions

Expert Solution

Golgi appratus does the targeting of all secreatory protein to their final destination. So any mutation in Golgi aparatus leads to severe nonfunctionality of different organ including neuron which leads to Parkinson disease and Alzimer disease.

In Alzimer disease it's been notice that the accumulation of harmful amyloid protein which cause ultimetly plaque on neuron or degrade the neuron cells and hence leads to loss of memory and other neurological diseases.

While in case of Parkinson's disease there is mutation in several genes which regulates antrigrade and reterigrade movt and hence protein distribution is not there and leads to accumulation of protein alpha sunuclein which affectes brain. Due to which certain part of brain which regulate movement become non functional.

Further Achondrgenesis is s disease in which there is short limb or bone formation takes place in case of mammals as microtubules formation is become defect that leads to defect in vesicle formation and hence transport of proteins. This leads to defective cartilage and bone formation.

Hopeclear..Thanks..

gladiator answered 1 year ago

Next > < Previous

Related Solutions

The powerhouse of the cell that generates ATP is Peroxisomes Mitochondria Plasma membrane Golgi body The...

The powerhouse of the cell that generates ATP is Peroxisomes Mitochondria Plasma membrane Golgi body The connective tissue disorder due to a mutation on chromosome 15 causing weak joints and ligaments is Tay-sachs disease Marfan syndrome Phenylketonuria Neurofibromatosis Carcinogenesis involves three stages. Which stage involves the induction of unregulated accelerated growth in susceptible cells? Initiation. Transduction. Promotion. Progression. Necrotic death of brain tissue usually produces Fat necrosis. Caseous necrosis. Liquefactive necrosis. Coagulative necrosis. Lack of exercise during an illness may...

what are the effect of anxiety disorders on human body?

What are some of the stigmas associated with mental disorders such as schizophrenia?

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection (PANDAS) is a group of disorders recently recognized...

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection (PANDAS) is a group of disorders recently recognized as a clinical entity. Do you agree that PANDAS could be autoimmune? Why or why not? Why do you think the rate of Group A beta-hemolytic streptococcus (GABHS) is so high in young child? Would you warn parents about PANDAS if they have a child with strep throat? Why or why not?

Overview Most disorders or diseases are caused by a combination of environmental and genetic factors

Overview Most disorders or diseases are caused by a combination of environmental and genetic factors. However, some are caused solely by genetics. We are going to examine the latter in this discussion. You will be given the choice of a genetic disorder to research and write about, and then you will draw some conclusions based on this information. You should spend approximately 3 hours on this assignment. Instructions Choose one genetic disorder from the following list: Sickle cell anemia...

Another disease caused by a mutation in a single gene is Huntington’s disease (HD), an autosomal...

Another disease caused by a mutation in a single gene is Huntington’s disease (HD), an autosomal dominant condition. It is caused by mutations in a gene required for normal nerve cell function. The mutations cause abnormal proteins to be produced which “stick” together and accumulate in nerve cells, eventually interfering with normal cell operations. Suggest two ways you could treat the disease by targeting the translation step for the HD protein and justify why each approach might be effective.

Include their function and the indication of an increased and decreased – what disorders are associated...

Include their function and the indication of an increased and decreased – what disorders are associated with high/low level, make sure to include signs and symptoms of the disorder/s. Acetylcholine Dopamine Gamma-aminobutyric acid (GABA) Glutamate Norepinephrine Serotonin

Describe in detail an example of a disease that is caused by an imbalance of estrogen...

Describe in detail an example of a disease that is caused by an imbalance of estrogen signaling.

The disease beriberi is caused by a deficiency of thiamine in the diet. Why is this...

The disease beriberi is caused by a deficiency of thiamine in the diet. Why is this disease often associated with metabolic acidosis and neurological disorders?

Exlpain the following: (a) Most genetic disorders that detrimentally affect survival or fertility are caused by...

Exlpain the following: (a) Most genetic disorders that detrimentally affect survival or fertility are caused by recessive mutations. Discuss the reasons for this, in terms of both gene function and natural selection. (b) However, there are some genetic disorders caused by dominant mutations. In light of your answers to part (a), how do these deleterious dominant mutations persist in a population?

Subjects