In: Biology
Immunology
Describe the two signals needed to activate B and T cells Describe the structure of a lymph node and relate this structure to the function of the lymph node in concentrating antigen and initiating an immune response.
Explain how an ELISA is used to quantify antibody concentrations and measure an immune response.
Understand how to interpret FACS data including side vs forward scatter, MFI values and multicolor staining profiles Distinguish between how B and T cells recognize antigens.
Describe the 4 mechanisms which contribute to B cell receptor diversity Detail the molecular regulation of VDJ recombination
Describe the formation of SMACs and their role in T cell activation What are ITAMs and what role do they play in the initiation of B and T cell recepetor signaling?