Question

Describe the major long-term limitations of bare metal intravascular stents. Provide an overview of stent development since the emergence of bare-metal stents and how

these limitations have been overcome.

Answer 1

In the case of metal intravascular stents, if you talk about the long term limit.

This can happen in many ways,

(a) metal intravascular stents cause permanent physical irritation risk of long term endothelial dysfunction and chronic inflammation.

(b) During the long period of metal intravascular stents cause thrombogenic properties.

(c) The inability of the vessel to restore its normal physiology during long term use.

(d) Their trackability decreases day by day over a long period of time.

(e) It is not as safe as biodegradable stents.
(f) It is also less in terms of flexibility than the biodegradable and balloon stents.

Provide an overview of stent development since the emergence of bare-metal stents and how

these limitations have been overcome.

it's completely done by, -the different drugs on the stents to combat restenosis.

- different drugs on the to increases endothelial healing.

- bioabsorbable stents.

- Stents with progenitor cells (stem cells)

- Gene therapy stents.

These limits can be crossed by including all these points.