Question

How does pollens and cold temperature contribute to the pathophysiology os asthma? Briefly explain.

Answer 1

How does pollens and cold temperature contribute to the pathophysiology os asthma? Briefly explain.

Pollen is the most common triggerer of asthma and the pathophysiology behind an asthma attack is the allergy. Thatswhy, pollen are known as allergen. Rain drops can crash into airborne pollen that contains tiny broken pollen particles. These allergens triggers the complex athophysiology of asthma by causing inflammation of airways, obstructive flow of air through the tubes and elicitating bronchial hyperresponsiveness. Symptoms like wheeze, cough, chest tightness and breathing difficulties are due to the antigen presentation by DC along with triggered lymphocyte and cytokine response for the allergen pollen. Worse asthma attack happens when larger pollen get into lungs.  

Cold air is dry and can trigger asthma attack. Cold dry air breathed in can evaporates faster than it can be replaced. It causesdryness in the airway passage which becomes irritated and swollen. Cold air also triggers the release of histamine, an important mediater of allergic reactions. All these together contribute for worsen asthma symptoms.