Question

PLZ type the answer for question one so I can read it easily. huge thumbs.

1-What are autologous cells, their benefits, and drawback

2- A man and a woman walk into a genetic counselor’s office. The woman has a brother who has been diagnosed with hemophilia, a sex-linked condition. The man has no family history of the illness. They are considering having children. Which of the following statements are appropriate and correct things to say to this couple?

1-The chance of any given child from this couple having hemophilia is approximately 50%

2-Assuming the woman and her afflicted brother have the same mother, the chance of a male child from this couple having hemophilia is approximately 25%

3-The chance of a female child from this couple having hemophilia is approximately 50%

4-An egg donor might be a good idea, if they are open to the idea

5-A sperm donor might be a good idea, if they are open to the idea

6-The two should probably adopt, and not spread their bad genes

Answer 1

Qn 1.

Autologous cells are own cells. In stem cell therapy autologous cell therapy is used. In this type of transplantation stem cells are removed and stored from a Patient and then receive their own cells .

This type of transplantation has low risk factor for rejection. Because an individual's own cell is transplanted.

Drawbacks are ,the collection procedure is painful for the patient. Large amounts of stem cell needs to be collected. Which is very painful so the patient must be hospitalized .

Qn 2.

Ans. Option 2. Assuming the woman and her afflicted brother have the same mother, the chance of a male child from this couple having haemophilia is approximately 25%.

Explanation:

The woman have an affected brother. Haemophilia is a X linked recessive disorder. So the genotype of her brother must be X^hY.

Their mother must be a carrier, her genotype is X^HX^h (H= normal , h = hemophilia).

Their father is normal, so his genotype is X^HY

So , the Probability of the woman to be a carrier(X^HX^h) is 50%.

Her husband is normal, so his genotype X^HY.

So the chance of the male child to be affected (half of 50%) is 25%.