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very emergence When glucose is transported into liver cells, it is modified. Name the type of...

very emergence

When glucose is transported into liver cells, it is modified.

  1. Name the type of modification to glucose.                                                                (1 mark)

________________________________________________________________________

  1. In which part of liver cell does this modification occur?                                          (1 mark)

________________________________________________________________________

  1. Name the enzyme in liver cells responsible for this modification.                           (1 mark)

________________________________________________________________________

  1. Name the enzyme in brain and muscle cells with the same activity.                        (1 mark)

________________________________________________________________________

  1. What is the significance of this type of modification?                                            

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  1. Give TWO differences between the enzymes described in (C) and (D).              

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Solutions

Expert Solution

When glucose is transported into liver cells, it is modified.

A. Name the type of modification to glucose.

Phosphorylation at hydroxyl group of position 6.

B. In which part of liver cell does this modification occur.

It occurs in the cytoplasm of liver cells.

C. Name the enzyme in liver cells responsible for this modification.

Glucokinase phosphorylates glucose at 6th position.

D. Name the enzyme in brain and muscle cells with the same activity.

Hexokinase phosphorylates glucose at 6th position.

E. What is the significance of this type of modification?

Phosphorylation of glucose traps it inside the cell preventing it from escape to outside.

F. Give TWO differences between the enzymes described in (C) and (D).

Glucokinase is present only in the liver and β-cells of the pancreas, while hexokinase is present in all the tissues.

Glucokinase requires high concentration of glucose (high Km) while hexokinase works even at low concentrations of glucose (low Km).

gladiator answered 2 years ago
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