1. You are interested in how cyclic-AMP-dependent protein kinase A (PKA) functions to affect learning and...

1. You are interested in how cyclic-AMP-dependent protein kinase A (PKA) functions to affect learning and memory, and you decide to study its function in the brain. It is known that activated PKA phosphorylates the transcriptional regulator called Nerd that then activates transcription of the gene Brainy. Give two possible mechanisms for increasing manipulating this pathway to increase Brainy expression.

2. What would be the result of the following—would the signaling pathway involving Gs and/or adenylyl cyclase be increased or decreased?

A.GTP not hydrolyzed on Gs

B.Gi (inhibits adenylyl cyclase) not functional

Expert Solution

gladiator answered 2 years ago

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