5. Patient with chronic heart failure is using digoxin (digitalis) for more than 1 year. Describe...

5. Patient with chronic heart failure is using digoxin (digitalis) for more than 1 year. Describe what effect has this treatment with digitalis have on the distribution of ions across the membrane of cardiac muscle cells? How digitalis helps to treat patients with heart failure?

Expert Solution

Digitalis, also called as digoxin or oubain is given to a person who has symptoms of chronic heart failure. It helps the weakened heart to pump the blood more effectively by improving the force of heart muscle contraction and restores the normal and steady heart rythm.

In the myocardium, the action of digitalis causes inhibition of Na⁺/K⁺ ATPase by binding to its extracellular part. The role of Na⁺/K⁺ ATPase is to keep the level of sodiumlow inside the cell by pumping three Na⁺ outof the cell for two K⁺ that are pumped in. The inhibition of Na⁺/K⁺ ATPase by digitalis increases the sodium levels inside the cell which in turn reduces the activity of Na⁺/Ca²⁺ exchanger which otherwise imports three Na⁺ into the cell in exchange of one calcium ion which is exported out of the cell. The overall result is the increase in cellular calcium levels that are stored by cells in sarcoplasmic reticulum. During action potential, there is an increased release of calcium which leads to increased contractibility or force of contraction of heart. In addition, increased intracellular calcium stretches the Phase 4 and Phase 0 of action potential leading to the decreased heart rate. This improves or relieves the patient from the symptoms of heart failure.

gladiator answered 2 years ago

Case Example: A 68-year-old man with diabetes and chronic congestive heart failure who is prescribed digitalis...

Case Example: A 68-year-old man with diabetes and chronic congestive heart failure who is prescribed digitalis and insulin presents to the emergency department with abdominal pain and cramping. Upon exam, the he is noted to have hyperactive reflexes. An ECG shows a prolonged PR interval, widened QRS and depressed ST segment. 1.What electrolyte imbalance is this patient most likely suffering from?

Your patient is an active 80-year-old woman with heart failure and chronic atrial fibrillation. You are...

Your patient is an active 80-year-old woman with heart failure and chronic atrial fibrillation. You are taking an angiotensin-converting enzyme inhibitor, a beta-blocker, a diuretic, and digoxin. During her evaluation, she tells him that she felt very dizzy this morning. How would you approach your evaluation and why? Identify some of the key evaluation factors. What nursing interventions are necessary? How would you change your evaluation and interventions if your patient also had chronic obstructive pulmonary disease and kidney failure?

Cardiotonic and Inotropic Drugs A 60-year-old patient who is administered digoxin has developed severe digitalis toxicity....

Cardiotonic and Inotropic Drugs A 60-year-old patient who is administered digoxin has developed severe digitalis toxicity. 1. What is the usual treatment for this condition? 2. What new drugs are being used to treat heart failure that reduce hospitalizations associated with chronic heart failure

How can adequate education for chronic heart failure patients using the patient portal encourage self-care management,...

How can adequate education for chronic heart failure patients using the patient portal encourage self-care management, prevent frequent hospital readmissions, and reduce healthcare costs.

(1) Explain Acute versus chronic conditions with patient with heart failure (2) Tissue integrity: Explain venous...

(1) Explain Acute versus chronic conditions with patient with heart failure (2) Tissue integrity: Explain venous stasis ulcer (3) What is the cause of leukemia?

For a congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD) patient, select one application...

For a congestive heart failure (CHF) or chronic obstructive pulmonary disease (COPD) patient, select one application or a technology that could effectively increase patient engagement and patient outcomes for your future practice area or work focus. What elements of this application or technology are the most valuable to you? How could you improve this technology?

6. Describe why older adults are more likely to develop acute or chronic renal failure.

Patient Teaching to a 79 years old patient who has heart failure and newly diagnosed 1....

Patient Teaching to a 79 years old patient who has heart failure and newly diagnosed 1. Create a patient scenario (3-4 sentence that describes your client's situation that necessitates teaching) 2. Assessment data indicating a learning need (include pertinent positive/negative data) 3. Nursing diagnosis that indicates the need for patient teaching (NANDA stem, r/t and AEB) 4. expected outcome (use action very and time frame in terms of the client) 5. methodology/tools (what equipment, instructions aids, method of communication) 6....

write 5 objectives and rationale for heart failure

. The patient was a 77-year-old female admitted with Congestive Heart Failure, and past medical history...

. The patient was a 77-year-old female admitted with Congestive Heart Failure, and past medical history of an Acute MI, four to six months before admission date. She had been taking Lasix 40mg PO BID and Cardizem 30 mg TID. In a report, I heard that her last O2 saturation was 77% on 3 liters via nasal cannula. Vital signs- afebrile, HR 108, RR 22, BP 148/88. She had an IV of D5W at KVO, the EKG was done, and...

Question