Question

In: Biology

A patient comes to you complaining about her inability to digest fats properly. She would like...

A patient comes to you complaining about her inability to digest fats properly. She would like you to explain to her how fats, carbs, and proteins are digested.(Answer in detail please)

Solutions

Expert Solution

i. Inability of digestion of fats properly in the given case would be due to deficiency of lipase, bile salts deficiency, malabsorption or fatty acid metabolism disorder.

ii.

a. Digestion of fats:

Area Juice Enzymes Substrates End product
Mouth Saliva Lingual lipase Triglycerides Fatty acid and 1,2 diacylglycerol
Stomach Gastric juice

Gastric lipase

(weak lipase)

Triglycerides Fatty acids and glycerol
Small intestine Pancreatic lipase Pancreatic lipase Triglycerides Monoglycerides, Fatty acid
Cholesterol ester hydrolase Cholesterol ester Free cholesterol and fatty acid
Phospholipase A Phospholipids Lysophospholipids
Phospholipase B Lysophospholipids Phosphoryl cholline, free fatty acids
Succus entericus Intestinal lipase Triglycerides Fatty acids and glycerol (weak action)

b. Digestion of Carbohydrates:

Part of Gastrointestinal tract Juice Enzyme Substrate End-product
Mouth Saliva Salivary amylase Polysaccharides Disaccharides-Dextin and maltose
Stomach Gastric juice Gastric amylase Weak amylase Action is negligible
Small intestine Pancreatic juice Pancreatic amylase Polysaccharides Disaccharides-Dextrin, maltose and maltriose
Succus entericus Sucrase Sucrose Glucose and fructose
Maltase Maltose and maltriose Glucose
Lactase Lactose Glucose and galactose
Dextrinase Dextrin, maltose and maltriose GLucose
Trehalase Trehalose Glucose

c. Digestion of proteins:

Part Juice Enzyme Substrate End product
Mouth Saliva No proteolytic enzyme --- ----
Stomach Gastric juice Pepsin Proteins Proteoses, Peptones, Large polypeptides
Small intestine Pancreatic juice Trypsin Proteoses and peptones Dipeptides, tripeptides, polypeptides
Chymotrypsin
Carboxypeptidases A and B Dipeptides, tripeptides, polypeptides Amino acids
Succus entericus Dipeptidases Dipeptides Amino acids
Tripeptidases Tripeptides
Amino peptidases Large polypeptides

So, the end products of digestio are glucose (from carbohydrates), amino acids (from proteins) and fatty acids and glycerol (from lipids)


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