In: Biology
Importance of disposable bioreactor system in the industry?
Disposable Systems, Disposable Bioreaactor, buffer make-up and
hold tanks, and attachments are gaining in popularity because they
can reduce risk of cross-contamination between batches while
providing flexibility, minimizing turnaround time, reducing
cleaning costs, and easing validation restrictions.
Bioreactors ensure cell survival through adequate delivery of
essential nutrients throughout the three-dimensional tissue
engineered construct. bioreactors can also guide tissue structure,
organization, and ultimately function through the application of
chemical and mechanical stimuli.
Disposable bioreactors, buffer make-up and hold tanks, and attachments are gaining in popularity because they can reduce risk of cross-contamination between batches while providing flexibility, minimizing turnaround time, reducing cleaning costs, and easing validation restrictions. Additionally, disposables typically have fewer connections (sterile boundary points) than fixed vessels which provide incrementally better FG protection.Generally, a disposable vessel is compared to a fixed stainless steel tank using the parameters listed in Table 13-3. While it’s feasible to create a side-by-side cost comparison, the other parameters may take precedence. In particular, you must confirm that the materials used in the disposable system are compatible with the process.