In: Anatomy and Physiology
Discuss the causes and the pathophysiology of Melanoma.
melanoma: Melanoma, the most serious type of skin cancer, develops in the cells (melanocytes) that produce melanin.the pigment that gives your skin its color. Melanoma can also form in your eyes and, rarely, in internal organs, such as your intestines.the exact cause of all melanomas are not clear. sometimes they develop from moles with concerning increases size,shape ,irregular edges ,color, itchiness, skin breakdown.
Causes: main causes is
1. UV radiation
Where skin cancer develops Melanoma occurs when something goes awry in the melanin-producing cells (melanocytes) that give color to your skin.Normally, the skin cells develop in a controlled and orderly way — healthy new cells push older cells toward your skin's surface, where they die and eventually fall off. But when some cells develop DNA damage, new cells may begin to grow out of control and can eventually form a mass of cancerous cells. Just what damages DNA in skin cells and how this leads to melanoma isn't clear. It's likely that a combination of factors, including environmental and genetic factors, causes melanoma. Still, doctors believe exposure to ultraviolet (UV) radiation from the sun and from tanning lamps and beds is the leading cause of melanoma.UV light doesn't cause all melanomas, especially those that occur in places on your body that don't receive exposure to sunlight. This indicates that other factors may contribute to your risk of melanoma.