Question

In: Biology

A mutation prevents expression of the CAP protein. Will the Lac operon be expressed when lactose...

A mutation prevents expression of the CAP protein. Will the Lac operon be expressed when lactose levels are high and glucose levels are low? Explain your reasoning.

Solutions

Expert Solution

When the level of glucose is high in the medium, the amount of cAMP is less. This prevents the formation of CAP cAMP complex. CAP cAMP complex binds to promoter so, that lac operon can be expressed. In the presence of glucose and absence of CAP cAMP complex, the operon does not express itself.

When the concentration of glucose decreases, lactose increases, the concentration of cAMP also increases. This leads to the formation of CAP cAMP complex. This binds to promoter and initiate the expression of lac operon.

But if CAP protein is not expresses inside the cell (as per the question), than CAP cAMP complex will not be formed. Without this complex, there will be no expression of lac operon even if lactose levels are high in the medium.

Please give a good rating.

gladiator answered 2 years ago
Next > < Previous

Related Solutions

Describe the likely effect on gene expression of a mutation in the lac operon: a) that...
Describe the likely effect on gene expression of a mutation in the lac operon: a) that delegate the operator b) that mutates the lacI gene inactivating the repressor c) that the promoter mutates in the -10 region
Question. Discuss the expression of structural genes in lac operon, when activator (CAP binding site) of...
Question. Discuss the expression of structural genes in lac operon, when activator (CAP binding site) of lac operon is mutated and growth medium is supplemented with only lactose (glucose is unavailable) as a carbon source. Support your discussion with a simple illustration including elements of lac operon.
1) 4pts - The presence of glucose in the environment prevents lots of lac operon expression,...
1) 4pts - The presence of glucose in the environment prevents lots of lac operon expression, while glucose’s absence greatly increases expression – discuss how ATP concentration, adenylyl cyclase, and CAP/cAMP and holoenzyme increase lac operon expression. 2) Discuss how promoters, enhancers and the TF proteins that interact with them are used in eukaryotic cells to control transcription of housekeeping genes versus cell specific/regulated genes? Be specific about everything’s role – what binds where and does what! A) 4pts -...
752. A mutation in the operator of the Trp operon prevents repressor protein binding. Will the...
752. A mutation in the operator of the Trp operon prevents repressor protein binding. Will the Trp operon be expressed when tryptophan levels are high? Explain your reasoning. 753. A mutation in the promoter of the Trp operon prevents sigma factor binding. Will the Trp operon be expressed when tryptophan levels are low? Explain your reasoning. 754. A mutation in the Lac repressor protein prevents it from binding to lactose. Will the Lac operon be expressed when lactose levels are...
The lac operon consists of several genes that encode enzymes required for metabolizing lactose. The expression...
The lac operon consists of several genes that encode enzymes required for metabolizing lactose. The expression of the lac operon is regulated by the presence of lactose and glucose. Q) Describe the regulation operon when the level of glucose is low and the level of lactose is high?
The lac operon consists of several genes that encode enzymes required for metabolizing lactose. The expression...
The lac operon consists of several genes that encode enzymes required for metabolizing lactose. The expression of the lac operon is regulated by the presence of lactose and glucose. Q) What changes could you make to the lac operon to make the transcription from it independent of the presence or absence of lactose?
The lac operon consists of several genes that encode enzymes required for metabolizing lactose. The expression...
The lac operon consists of several genes that encode enzymes required for metabolizing lactose. The expression of the lac operon is regulated by the presence of lactose and glucose. Q) describe the regulation operon when the level of glucose is high and the level of lactose is high?
How might the presence/absence of lactose affect the lac operon expression in the context of glucose-mediated...
How might the presence/absence of lactose affect the lac operon expression in the context of glucose-mediated catabolite repression?
A cis-acting mutation that leads to MINIMAL expression of the lac operon would most likely be...
A cis-acting mutation that leads to MINIMAL expression of the lac operon would most likely be in the CAP binding site. Is this true or false, and why? Thanks!
3. Explain what happens to the Lac operon when lactose is present and glucose is also...
3. Explain what happens to the Lac operon when lactose is present and glucose is also present. Then explain what happens when lactose is present but glucose is absent. In your answer, include all of the components of the Lac operon and the molecules involved in its regulation. What is the protein product of the Lac operon? Explain why this mechanism of control is adaptive.
ADVERTISEMENT
Subjects
ADVERTISEMENT
Latest Questions
ADVERTISEMENT