Question

Question 3: Genetics and molecular biology of sleep:

Reverse genetics (starting from gene and progressing to phenotype, such as by cloning a gene and creating a knockout mouse) and forward genetics (starting from phenotype and progressing towards the genes, such as by mutagenesis followed by mapping and gene cloning) are experimental approaches that have been useful in many fields including improved understanding of the circadian pacemaker. Briefly discuss a couple successes of these approaches applied towards understanding sleep, and then discuss how you might use these approaches in Drosophila, mice, or humans, to better understand sleep regulation, sleep homeostasis, and/or sleep functions.

Answer 1