How is the usage of fat as an energy source regulated, and what would you expect...

How is the usage of fat as an energy source regulated, and what would you expect to be the effect of caffeine or theophylline on fatty acid mobilization?

Expert Solution

The Fatty acids are most abundant source of endogenous energy substrate. They can be mobilized from peripheral adipose tissue and transported via the blood to active muscle.

During higher intensity exercise, triglyceride within the muscle can also be hydrolyzed to release fatty acids for subsequent direct oxidation.

The process of lipolysis normally provides free fatty acids (FFA) at a rate in excess of that required to supply resting energy requirements.The large increase in FFA turnover after caffeine ingestion was probably due to the combined effects of caffeine on β-adrenergic lipolytic stimulation and on antagonism of the antilipolytic effects of adenosine.

The result of caffeine on lipid mobilization in resting situations can be taken in two ways:

lipid mobilization is inadequate to drive lipid oxidation.
large increments in lipid turnover result in small growths in lipid oxidation.

the mechanism of control of fatty acid oxidation in the muscle is the rate of entry into the mitochondria. generally the rate of glycolysis is the predominant regulator of the rate of carbohydrate metabolism in muscle, and that a rapid rate of carbohydrate oxidation caused by mobilization of muscle glycogen during high intensity exercise prevents fatty acid oxidation by preventive transport into the mitochondria

Caffeine ingestion enlarged energy expenditure 13% and doubled the turnover of lipids, of which 24% were oxidized and 76% were recycled

queen_honey_blossom answered 2 years ago

What are some different types of data you would expect to manipulate, and how would you...

What are some different types of data you would expect to manipulate, and how would you represent them in a program?

what is the difference between vegetable oil and fat? How would you describe the physical state...

what is the difference between vegetable oil and fat? How would you describe the physical state of fat and vegetable oil at room temperature?

How would you expect the latencies and amplitudes in the skin of the hand and the...

How would you expect the latencies and amplitudes in the skin of the hand and the foot compare? Explain any differences in the latencies.

What information would you expect to be collected in an auditing tool? What purpose would that...

What information would you expect to be collected in an auditing tool? What purpose would that information serve? What would that information tell you about your network health?

a. Would you expect companies that adopt ABC to add value to shareholders? How would you...

a. Would you expect companies that adopt ABC to add value to shareholders? How would you measure such added value? b. Accountants need to identify four steps in activity-based costing. What are the four steps?

What is the difference between symmetric competition and asymmetric competition? How would you expect species to...

What is the difference between symmetric competition and asymmetric competition? How would you expect species to react, adapt and evolve in response to each type of competition?

What are core values? How would you expect core values to show up in a company’s...

What are core values? How would you expect core values to show up in a company’s international expansion?

Why are financial institutions regulated? How are they regulated? What are liabilities of depository institutions? What...

Why are financial institutions regulated? How are they regulated? What are liabilities of depository institutions? What are the assets of depository institutions? How can depository manage the risk associated with each? What are depository institution regulated even more than other financial institutions?

5. How would you expect the expansion of Medicaid to affect the market for healthcare? Would...

5. How would you expect the expansion of Medicaid to affect the market for healthcare? Would it increase supply or demand? What would you expect to happen to the utilization of healthcare and the price of healthcare?

Summarize what you learned from the IMF article about public investment. How would you expect an...

Summarize what you learned from the IMF article about public investment. How would you expect an increase in spending on private investment to impact the debt/GDP ratio for the U.S.?

Question