Question

In: Anatomy and Physiology

You are a researcher interested in studying Schwann cell development. It is known from prior work...

You are a researcher interested in studying Schwann cell development. It is known from prior work that Schwann cells express the protein Sox10. You decide to create a transgenic fish line to label the Schwann cells. Explain how you would create the transgenic embryos. Be as detailed as possible.

Solutions

Expert Solution

* Transgenic embryos are created by genetic manipulation of host species that carry exogenous genetic material or genes from other species in their genome.

* This technique is used to introduce new genes or genes of interest into strains of laboratory to study function and pathology regarding specific gene.

* Fish is the first genetically modified animal to be used for consumption in humans.

* The fish is essentially an Atlantic salmon with single gene complex inserted, a growth hormone regulating gene from chinook salmon with a promoter sequence.

* The aim is to introduce new trait to fish that before does not occur in nature as a species. This process is called trans genesis.

* Genetically modified fish are developed as environmental pollutant sentinels and also used in aquaculture for production of food.

Transgenic fish are used in research centers

* Indicators of aquatic pollutants.

* used in functional genomic studies.

* Development in biomedical use as reactors for important proteins, used in cardiovascular diseases etc.


Related Solutions

A researcher was interested in studying the phenomenon known as social distance, the reluctance of people...
A researcher was interested in studying the phenomenon known as social distance, the reluctance of people to associate with members of different ethnic and racial groups. She designed an experiment in which students enrolled in a lecture course were asked to choose a discussion group (all meeting at the same time in the same building) based only on the ethnic–racial stereotype associated with the names of the teaching assistant: Group Teaching Assistant Room Enrollment A Cheng 106 12 B Schultz...
You are interested in studying the effects of a drug that is known to inhibit learning...
You are interested in studying the effects of a drug that is known to inhibit learning and memory functioning. You have decided that you will use rats, rather than humans, in your study. a. Which neurotransmitter is the drug likely affecting and why? b. Which research method would you use to study this and why would you choose that particular method over another? If this method were unavailable, describe another method you could use and why you would choose this...
1. The researcher from the Annenberg School of Communications is interested in studying the factors that...
1. The researcher from the Annenberg School of Communications is interested in studying the factors that influence how much time people spend talking on their smartphones. She believes that gender might be one factor that influences phone conversation time. She specifically hypothesizes that women and men spend different amounts of time talking on their phones. The researcher conducts a new study and obtains data from a random sample of adults from two groups identified as women and men. She finds...
The researcher from the Annenberg School of Communications is interested in studying the factors that influence...
The researcher from the Annenberg School of Communications is interested in studying the factors that influence how much time people spend talking on their smartphones. She believes that gender might be one factor that influences phone conversation time. She specifically hypothesizes that women and men spend different amounts of time talking on their phones. The researcher conducts a new study and obtains data from a random sample of adults from two groups identified as women and men. She finds that...
A researcher is interested in studying the effect that the amount of fat in the diet...
A researcher is interested in studying the effect that the amount of fat in the diet and amount of exercise has on the mental acuity of middle-aged women. The researcher used three different treatment levels for the diet and two levels for the exercise. The results of the acuity test for the subjects in the different treatment levels are shown below. Diet Exercise <30% fat 30% - 60% fat >60% fat <60 minutes 4 3 2 4 1 2 2...
A researcher is interested in studying the effect that the amount of fat in the diet...
A researcher is interested in studying the effect that the amount of fat in the diet and amount of exercise has on the mental acuity of middle-aged women. The researcher used three different treatment levels for the diet and two levels for the exercise. The results of the acuity test for the subjects in the different treatment levels are shown below. Diet Exercise <30% fat 30% - 60% fat >60% fat <60 minutes 4 3 2 4 1 2 2...
Scenario: Imagine you are a researcher who is interested in studying whether sleep deprivation leads to...
Scenario: Imagine you are a researcher who is interested in studying whether sleep deprivation leads to increased reaction times (i.e., being slower) when driving. You randomly select a sample of 30 licensed drivers. Fifteen participants are randomly assigned to get 5 hours of sleep for three consecutive nights. The other 15 participants are randomly assigned to get 8 hours of sleep for three consecutive nights. For the purposes of this Assignment, assume that all participants sleep exactly the required amounts....
A researcher at the Annenberg School of Communication is interested in studying the use of smartphones...
A researcher at the Annenberg School of Communication is interested in studying the use of smartphones among young adults. She wants to know the average amount of time that college students in the United States hold a smartphone in their hand each day. The researcher obtains data for one day from a random sample of 25 college students (who own smartphones). She installs an app that registers whenever the smartphone is being held and the screen is on. The sample...
A researcher was interested in the anxiety present in students just prior to the midterm exam....
A researcher was interested in the anxiety present in students just prior to the midterm exam. The research used an anxiety self-quiz to gage the student's anxiety. The score for 30 students are: 69,61,84,99.66.86.91.94,54,66,77,48, 70,70,86,98.56,43,70,88,78,53,85, 40,86,79,58,40,89,70. 1. Construct a frequency table with class, frequency, relative percent and cumulative percent that has 6 classes to describe the distribution of the data. 2. Use the frequency table to construct a histogram. 3. Calculate the numerical descriptive statistics mean, median, standard deviation, and...
1. You are studying a particular type of lung cancer, small-cell lung carcinoma. You are interested...
1. You are studying a particular type of lung cancer, small-cell lung carcinoma. You are interested on driver mutations of this cancer, that is mutations that provide strong selection advantage and thus have strong potential in initiating tumorigenesis. You have access to primary tumor biopsies from patients, and healthy surrounding tissue: how you can best use these tissue samples to identify mutations underlying this particular type of lung cancer? 2. The mutation you isolated has not been characterized before; how...
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT