For a pharmalogical experiment you need 1L of a drug at a concentration of 10x10-6 in...

For a pharmalogical experiment you need 1L of a drug at a concentration of 10x10-6 in saline. You have aliquots of a stock solution at a concentration of 10mM. How do you make the working solution?

Expert Solution

Stock solution required solution

concentration = M1= 10mM = 10 x10^-3M =10^-2M concentration = M2= 10 x10^-6M = 10^-5M

Volume = V1= volume = V2 = 1L = 1000 mL

for dilution

M1V1=M2V2

10^-2 x V1 = 10^-5 x 1000

V1 = 1 mL

we take 1mL of 10mM stock solution and add 999 mL of water to convert 1000mL (Or) 1L of dilution solution

queen_honey_blossom answered 1 year ago

You have made 1L of a 0.1M HEPES buffer, and now you need to adjust the...

You have made 1L of a 0.1M HEPES buffer, and now you need to adjust the pH to 7.7. Calculate how much of a 0.5 M NaOH solution you would need to add. I was told to use Henderson-Hasslebach, I'm not sure how to do this one

EXPERIMENT #6 DETERMINATION OF THE CONCENTRATION OF TARTARIC ACID IN WINE 1. Why must the sodium...

EXPERIMENT #6 DETERMINATION OF THE CONCENTRATION OF TARTARIC ACID IN WINE 1. Why must the sodium hydroxide concentration be reported to four significant figures? Why not use only two significant figures? 2. In the procedure, you added approximately 15 mL of water to each Erlenmeyer flask. Why did the exact volume of water not matter? What impact would accidentally adding 17 mL of water have on the results? Be prepared to explain. 3. Explain the significance of the value for...

- - - - - design an experiment to determine the concentration of HbA1c in the...

- - - - - design an experiment to determine the concentration of HbA1c in the blood sample by following these six steps Step 1, pick one differentiating characteristic Step2 how will u probe that differentiating characteristic Step3 tell the anticipated response to the probe step4 measure the response to the probe step 5 how will u interpret the response to the probe to obtain the desired information step6 tell the likely interference with the method you have chosen. you...

Suppose you are conducting an experiment and inject a drug into three mice. Their times for...

Suppose you are conducting an experiment and inject a drug into three mice. Their times for running a maze are 8, 10, and 15 seconds; the times for two control mice (i.e. not injected with the drug) are 5 and 9 seconds. Perform a two-sided permutation rest to determine if there is a statistically significant difference between mean maze completion time with the drug and without the drug.

What does a drug need to be soluble in water? What does a drug need to...

What does a drug need to be soluble in water? What does a drug need to be permeable to tissues? What will happen if the solubility of my drug changes over time?

You are a microbiology lab technician and you need to quantify the viable cell concentration in...

You are a microbiology lab technician and you need to quantify the viable cell concentration in your stock culture before beginning an experiment. Since you do not know the range, you perform a serial dilution over several orders of magnitude. You use the pour plate method and plate 1 ml for each dilution level, in duplicate. Give the most accurate value for the number of viable cells in the original stock culture, in CFU / ml. Just enter a number,...

7. You plan to conduct an experiment to test the effectiveness of Sleepze, a new drug...

7. You plan to conduct an experiment to test the effectiveness of Sleepze, a new drug that is supposed to reduce insomnia. You have a sample of 100 subjects. a. Why is it important to include a placebo in this experimental design? b. Describe how you can make this a completely randomized experiment. c. What is “blinding” and how might it be used in this experiment? d. Why is it important to use blinding in this experiment?

A) For an experiment you are doing in lab, you need 50.0mL of a 2.50 x...

A) For an experiment you are doing in lab, you need 50.0mL of a 2.50 x 10-2 M solution of Ni(NO3)2. Describe how you would prepare this solution from solid nickel nitrate and water to make the most accurate and reproducible solution as possible. Include any necessary calculations and a description of each step you would follow in the lab. Indicate what items you would use from the “tool-box” shown on the next page. (Please limit your description toeightsentences or...

a drug is given at an infusion rate of 50 mg/h. The drug concentration value determined...

a drug is given at an infusion rate of 50 mg/h. The drug concentration value determined that at 3 hours after the start of the infusion is 8mg/L. Assuming the patient has 5L of blood, estimate the half-life of this drug

You need to determine the concentration of a sulfuric acid solution by titration with a standard...

You need to determine the concentration of a sulfuric acid solution by titration with a standard sodium hydroxide solution. You have a 0.1539 M standard solution. You take a 25.00 mL sample of the original acid solution and dilute it to 250.0 mL. You then take a 10.00 mL sample of the dilute acid solution and titrate it with the standard solution. You need 12.23 mL of the standard solution to reach the endpoint. What is the concentration of the...

Question