Question

For IEUBK Model) 1.What assumptions are made when using this type of model? That is what values or relationships must the model include, which you did not supply. 2.What are the model supplied (“fixed") parameters which are assumed? 3.What are the user-supplied input variables required to run the model?

Answer 1

IEUBK Model stands for Integrated Exposure, Uptake, Biokinetic Model.

1. This model is used for determining the exposure levels of various contaminants in the young populations. Generally the most studied contaminant is lead. Lead concentrations in soil, dust, air, food, and other sources are studied in order to analyse the level of exposure of children. Various assumptions are made while studying the model.

a) How much of the ingested or inhaled lead is actually absorbed in the body

b) How much of the absorbed lead enters each of the different 'compartments' of the body.

c) how rapidly lead is removed from the body by excretion in urine or feces.

2. Model supplied parameters that are assumed are

a) lead concentrations or lead intakes from all environmental media or other lead exposure sources.

b) Human exposure to lead environment

c) Pharmacokinetic parameters for lead

3. User supplied input variables are exposure to soil, dust, air Pollution level.

For more information you can refer to the Environment Protection Agency Website which has underlaid guidelines for using the IEUBK Model