Neither Tsar Nicholas II nor his wife Empress Alexandra had the disease known as hemophilia, characterized...

Neither Tsar Nicholas II nor his wife Empress Alexandra had the disease known as hemophilia, characterized by being linked to sex. Her daughter, the princess Anastasia didn't have it either, but Zarevich Alexius, her brother, did.
a) Can it be assumed that Anastasia was "carrier" of the information for the hemophilia?
b) Why?
c) If she had married her cousin Henry, who was a hemophiliac, would it have been any of your sons or daughters? Specify possible cases

Expert Solution

Hemophilia is X linked disease, if mother is affected then son will definitely be diseased and if father is diseased then daughter will be carrier. Chances of female being diseased is very less, if both the paerent are diseased then their daughter will be diseased. Below chart has shown the three cases.

According to the question husband and wife both are normal but their son is diseased not their daughter, this mean that definitely mother would be a carrier. Anastasia could be carrier or could be not, there are 50% chance of both as mother has one normal X and one carrier X gene.

If Anastasia have married henry who is diseased then there are two probability if anastasia is carrier and if she is normal

This is the probability of getting their son or daughter diseased.

gladiator answered 1 year ago

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