A hybridoma results from the fusion of a(n)___ a.myeloma cell with a virus. b.B cell with...

A hybridoma results from the fusion of a(n)___

a.myeloma cell with a virus.

b.B cell with a myeloma cell.

c.antigen with an antibody.

d.antigen with a B cell.

e.B cell with a T cell.

Expert Solution

B ) hybridoma results from the fusion of B cell with a myeloma cell .

Explanation -

In this modern era of medicine , a lot of new therapies have come up ,one of which is immunotherapy which utilizes monoclonal antibodies ( antibodies specific to a particular protein or cell ).

For eg. Therapeutic monoclonal antibodies-

1.Trastuzumab (herceptin) is used in particular type of breast cancer .

2. Rituximab (acting against the Cd20 surface protein on B cells ) is used in a number of diseases like rheumatoid arthitis etc.

Monoclonal antibodies can also be used for diagnostic purposes

These monoclonal antibodies can be produced using the HYBRIDOMA technique , in which an immune B cell (which produces antibodies against a particular antigen/protein- monoclonal) is fused with a cancer (myeloma ) cell. This fusion results in the formation of HYBRIDOMA, a hybrid cell with properties of both monoclonal B cell ( monoclonal antibody synthesis) and the myeloma cell ( rapid proliferation) and thus , this cell (HYBRIDOMA ) proliferates rapidly leading to formation of monoclonal antibodies.

gladiator answered 2 years ago

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