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Learning Objective 3 – Identify the Design of a particular study 1) To determine if conversations...

Learning Objective 3 – Identify the Design of a particular study



1) To determine if conversations about HIV status decreases the risk of acquiring HIV among men having sex with me (MSM). From March 2008 through May 2010, persons newly diagnosed with HIV-positive men and HIV-negative men were recruited by researchers. To distinguish recent (<5 months) from longstanding (>5 months) infection, dried blood spots from people newly diagnosed with HIV were tested with the BED IgG-capture ELISA. HIV-positive men and the matched HIV-negative men completed a knowledge, attitudes, behavior and practices (KABP)-questionnaire. Researcherscompared HIV-positive men with recent infection and matched HIV-negative men among men having sex with men (MSM) regarding reported risk behavior in the previous 6 months.  What type of study is this? Explain.What are its strengths and limitation?

2) Tumors of the central nervous system are the second most common group of childhood cancers in 0-14 year olds (24% of total cancers) and represent a major diagnostic group in 15-24 year olds. Researchers were interested in learning if breastfeeding was a protective factor in such tumors. Researchers identified children with a newly diagnosed intracranial tumor. All patients were recruited from one major clinical cancer treatment center. Children with brain tumors were matched to children without brain tumors that were of similar age, sex, and BMI. These healthy children were drawn from general practice lists. What type of study is this? Explain. What are its strengths and limitation?

3) A previous review showed that high stress increases the risk of occupational injury by three to five-fold. Researchers examined the effect of stress on recorded hospitalized injuries over a period of 8 years. A total of 16,385 employees of a logging company responded to the questionnaire. Perceived stress was measured with a validated single-item measure, and analyzed in relation recorded hospitalized injuries from 1986 to 2008. What type of study is this? Explain. What are its strengths and limitations?

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