Which of the following genes is responsible for direct suppression of BMP during limb growth? Group...

Which of the following genes is responsible for direct suppression of BMP during limb growth?

Group of answer choices

a, Wnt3a

b. Fgf10

c. Fgf8

d. Shh

e. Gremlin

Expert Solution

Answer: c. Fgf8

Explaination:

Bone morphogenetic proteins (BMPs) are a group of proteins proteins that promote the formation of bone and the skeleton and help in healing of broken bones. BMP signaling is very important for limb development. The early inhibition of BMP signqling leads to the formation of distally truncated limbs, whereas later inhibition causes polydactyly and increased number of digits. The apical ectodermal ridge (AER), a structure formed at the distal intersection of the dorsal and ventral ectoderm, expresses four FGF genes (Fgf4, Fgf8, Fgf9, Fgf17). Among these three genes are redundant but Fgf8 is the most important, as it is widely expressed and can maintain relatively normal limb development even in the absence of the other three genes. AER and FGF genes are involved in promoting distal fates as well as in mediating several processes during limb development.

Thus the answer is “c. Fgf8” gene is responsible for direct suppression of BMP during limb growth.

gladiator answered 2 years ago

which of the following substituents will direct the incoming group to the ortho/para position during electrophilic...

which of the following substituents will direct the incoming group to the ortho/para position during electrophilic aromatic substitution a) -NO2 b) -CF3 c)-Br d) -COOCH3 e) -COCH3

Which of the following is NOT an argument against economic growth? Group of answer choices Growth...

Which of the following is NOT an argument against economic growth? Group of answer choices Growth may deplete resources. Growth is often inequitable. Growth has negative environmental impacts. Growth leads to an expansion of power.

Which of the following is FALSE regarding hox Genes? Group of answer choices They serve the...

Which of the following is FALSE regarding hox Genes? Group of answer choices They serve the role of defining segmental regions along the anterior to posterior axis during development Their functions have diversified through gene duplications followed by differentiation (e.g. subfunctionalization), leading to differentiation of segmental regions in animals They encode transcription factors that perform trans-regulatory functions They are responsible for the major body plan differences among animal phyla

Which of the following is a relatively direct determinant of market structure? Group of answer choices...

Which of the following is a relatively direct determinant of market structure? Group of answer choices economies of scale the possible influence of medium-sized firms the possible influence of the smallest firms the influence of small firms

Question 50.5 pts Which of the following is NOT a major advantage of direct finance? Group...

Question 50.5 pts Which of the following is NOT a major advantage of direct finance? Group of answer choices Direct finance allows borrowers to diversify sources of funds. potentially reduced cost for borrowers. Direct finance reduces search and transactions costs. Direct finance allows greater flexibility in funding types. Flag this question Question 60.5 pts Calculate the effective annual interest rate if your bank quotes you 10% per annum, compounded quarterly. Group of answer choices 2.50% 14.01% 10% 10.38% Flag this...

What hormones are responsible for the growth spurt during puberty? What cells do these hormones target...

What hormones are responsible for the growth spurt during puberty? What cells do these hormones target and what is the action of these cells? Be clear and specific. Explain why there is a risk of stunted growth to a teenage male by taking anabolic steroids. Anabolic steroids mimic the effects of testosterone a sex hormone. Be clear and specific in the effect on bone growth. A post-menopausal woman will have a significant decrease in estrogen levels. Explain why this will...

Which of the following statements about global economic growth is NOT true? Group of answer choices...

Which of the following statements about global economic growth is NOT true? Group of answer choices In 2010 it was noted that, globally, banks faced a "wall" of maturing debt. The economic struggles of large economies impact the global economy more than those of small economies. The credit crisis started in 2008 and increased in 2009. From 1980 to 2012 China has had the largest economy and rate of expansion.

Which group of pacemaker cells is responsible for setting the heart rate in a healthy patient?...

Which group of pacemaker cells is responsible for setting the heart rate in a healthy patient? Write a flow diagram (eg: structure A --> structure B --> structure C, etc.) to describe the path that an action potential would take as it makes its way through the electrical conduction system of the heart, being sure to name all structures. What structure enables action potentials to directly spread between neighbouring cardiomyocytes? Be specific.

During the embryogenesis, axial mesoderm cells are specialized to express different genes. We identified three group...

During the embryogenesis, axial mesoderm cells are specialized to express different genes. We identified three group of cells present in close proximity. Among these groups one cell subtype (known as Sub1) have probability of 0.5 to express gene XRA. The other cell subtypes (known as Sub2 and Sub3) have a probability of 0.8 and 0.1 respectively. Suppose that we isolated one of these cell subtypes at random and grow them in the lab to study gene expression patterns. We define...

3a)Which group of the following manufacturing cost elements occurs in a process cost system? a. Direct...

3a)Which group of the following manufacturing cost elements occurs in a process cost system? a. Direct labour and direct material. b. Direct labour and conversion costs. c. Direct materials, direct labour, and manufacturing overhead. d. Manufacturing overhead and conversion costs. 3b) For which one of the following would a process cost system most likely be used? a. cruise ships b. motion pictures c. potato chips d. custom furniture 3c) The primary benefit of ABC is it provides a. more accurate...

Question