Question

Individuals who receive radiation exposure or chemotherapy may be at increased risk of later developing primary bone cancer (meaning that the cancerous growth starts in the bone). Using your knowledge of the formation of bone and the overall function of skeletal tissue in the body, explain why this is not surprising.

Answer 1

• The human body consist of 206 skeletal bones and made skeletal system
• The main function of Bones is protect the internal organs, allow people to stand upright, and attach to muscles, which allow movement.
• Bones are connected to other bones by bands of tough, fibrous tissue called ligaments.
• Cartilage are the smooth elastic tissue covers and protects the joints where bones come together.
• Bones are hollow and filled with bone marrow, it is the spongy, red tissue

Types of bone cells

1. Osteoclasts
2. Osteoblasts which build new bone
3. Osteocytes that carry nutrients to the bone

Bone cancer

• Bone Cancer develop when healthy cells in the bone change and grow out of control.
• Generally primary bone cancer is rare. It common when other cancers, such as breast, lung, or prostate cancer, to spread to the bone and also as a result of radiation and chemotherapy
• Radiation treatment for other cancerous conditions have a greater risk of developing bone cancer at the site of the radiation therapy. The majority of radiation therapy-caused sarcomas include angiosarcoma and undifferentiated pleomorphic sarcoma of soft tissue or osteosarcoma
• Some drugs like alkylating agents and anthracyclines use for chemotherapy are may increase the risk of developing a secondary cancer, usually osteosarcoma.
• Radiation cause bone cancer is mainly due to high exposure to radioactive materials such as radium and strontium can also cause bone cancer because these minerals build up in bonebones so it leads to abnormal growth of bone