In: Biology
Walk through the the process for how nucleotides and ribose are made and show how these come together to make ATP used for DNA replication. You must start from glucose and CO2 as your starting materials, everything else must be made from these compounds. Would appreciate answer with drawing as well as written explanation.
When CO2 and glucose used as starting material. The glycolysis pathway is used to convert te glucose into glyceraldehyde 3 phosphate (GAP). The GAP is converted into xylulose 5 phosphate and the Glucose 6 phosphate is converted into Ribulose 5 phosphate. This GAP is also used to form Ribose 5 phosphate. The formed ribose sugar is then used in the synthesis of nucleotide.
The nucleotide biosynthesis involves the use of ribose sugar and with the number of enzymes, the sugar is converted into Inosine monophosphate. IMP is the precursor for the purine biosynthesis.
The IMP is then acted by enzymes and AMP is formed and with the subsequent addition of inorganic phosphate, the AMOP is converted into ATP.